Human papilloma virus (HPV) vaccines are vaccines that prevent infection by certain types of human papillomavirus.[1] Available vaccines protect against either two, four, or nine types of HPV.[1][2] All vaccines protect against at least HPV 16 and 18 that cause the greatest risk of cervical cancer. It is estimated that they may prevent 70% of cervical cancer, 80% of anal cancer, 60% of vaginal cancer, 40% of vulvar cancer, and possibly some mouth cancer.[3][4][5] They additionally prevent some genital warts with the vaccines against 4 and 9 HPV types providing greater protection.[1]